None of the other victims was wearing an oxygen mask, the public prosecutor added. The mask was from a Boeing 777 plane, but it was unknown how and when it had been put on.
Mr Timmermans is seen as one of the big hitters in the Dutch government.
He is due to leave his post shortly as foreign minister to take up a post as European Commission President Jean-Claude Juncker's right-hand man.
He mentioned the oxygen mask during an interview with Jeroen Pauw, in which he was taken to task for an emotive speech he gave to the UN four days after flight MH17 was downed on
17 July.
Final moments
In his address to the Security Council, Mr Timmermans imagined the horror felt by the passengers "when they knew the plane was going down" and wondered whether they had looked each other in the eyes "one final time, in an unarticulated goodbye".
When asked on Wednesday night if he had created an image that had not really taken place, Mr Timmermans said: "Oh yes? Can you be so sure about that?"
He acknowledged that those on board would not have seen the missile hit the plane.
"But do you know that someone was found with an oxygen mask on their mouth - and so they had the time to put it on?" Mr Timmermans said.
He went on to say that nothing could be ruled out about the 298 victims' final moments.
The official inquiry into the MH17 disaster had not made any mention of an oxygen mask being found on one of the victims.
But several experts concluded that the plane would have disintegrated too quickly for the passengers to have known anything about it.
Victims' families, angry that they had not been told about the oxygen mask before, were told by prosecutors that an inquiry was still being carried out and no conclusions had been drawn.
Mr Timmermans, who was due to give a statement to parliament on the matter, said in his statement that the disaster was close to his heart. "I sympathise enormously with the relatives," he said.
Although investigators were unable to visit the crash site because of fighting in the area, their initial report pieced together photographic evidence of the wreckage as well as cockpit and air traffic control data.
They said it pointed to "an in-flight break up" and added there was "no evidence of technical or human error".
The plane was hit while flying at 33,000ft (10,000m) and debris was found over a wide area of eastern Ukrainian territory held by pro-Russian
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